ICU delirium
Delirium in intensive care: risk factors, sedation issues, and evidence‑based prevention.
ICU delirium
Delirium in intensive care: risk factors, sedation issues, and evidence‑based prevention.
Key points
- ICU delirium is common and linked to longer ventilation and worse outcomes; prevention is active daily work.
- Minimize deep sedation, promote day–night cues, early mobility, and pain-first analgesia.
- Treat hypoxia, sepsis, and withdrawal promptly; review sedatives and anticholinergics.
Clinical scenario
A patient develops abrupt changes in attention, behavior, or sleep–wake rhythm. Symptoms fluctuate, and caregivers report either agitation or unusual quietness and withdrawal.
What this usually means
In the ICU, delirium is driven by critical illness, sedatives, immobility, sleep disruption, and isolation. Daily sedation interruption, early mobility, and reorientation reduce burden.
What to check systematically
Collect: exact onset and fluctuation pattern; baseline cognition and independence; new symptoms (fever, cough, dysuria, pain, dyspnea); fluid intake and urine output; bowel pattern; alcohol use; and a complete medication list including supplements and OTC products. In medical settings, typical initial tests include vitals, oxygenation, glucose, basic labs (electrolytes, kidney/liver function), urinalysis when indicated, and focused imaging based on exam.
Management priorities
First address immediate threats (oxygenation, glucose, hemodynamics) and treat pain and infection promptly. Remove triggers: stop or reduce deliriogenic medications where possible, correct dehydration/electrolytes, treat constipation/urinary retention, and restore sleep cues. Use calm, repeated reorientation and involve family; avoid restraint unless absolutely necessary. If medication is required for severe agitation or hallucinations causing danger, use the lowest effective dose and review daily.
Prevention & recovery
Maintain routines, hydration, mobility, and sensory aids. After an episode, schedule a medication review and plan delirium prevention for future hospitalizations or surgeries. Monitor for persistent cognitive symptoms and seek reassessment if confusion does not steadily improve.
Practical tables
| Common contributor | Clues | Practical action |
|---|---|---|
| Medication effect/interaction | New drug or dose change; OTC sleep/cold remedies | Review all medicines; ask clinician about deprescribing |
| Infection | New weakness, urinary changes, cough; may lack fever in frail adults | Same-day medical evaluation |
| Dehydration | Low intake, dry mouth, reduced urine | Encourage fluids if safe; assess for IV fluids if needed |
| Hypoxia | Shortness of breath, low SpOâ‚‚ | Urgent assessment; oxygen as directed |
| Pain/retention/constipation | Restlessness, guarding, minimal stool/urine | Treat pain; address bladder/bowel triggers |
| Communication tip | Why it helps |
|---|---|
| One idea per sentence, slow pace | Attention is impaired—reduce cognitive load |
| Use clocks, calendars, daylight | Restores orientation and circadian rhythm |
| Confirm hearing aids and glasses | Reduces misinterpretation and hallucinations |
| Mobilize safely every day | Improves sleep, reduces pneumonia/constipation |
| Keep nights quiet and dark | Sleep protection lowers delirium severity |
Related topics
Causes of delirium • Diagnosis and treatment • Prevention • When to seek urgent care